Decode the Immune Signature of Disease
We're developing next-generation immune profiling technologies to transform how autoimmune diseases are diagnosed—enabling earlier intervention and better patient outcomes.
The Diagnostic Challenge
Millions of patients with autoimmune diseases face years of diagnostic uncertainty. Current tests often can't distinguish who will develop disease from who won't.
Of diagnostic delay for many autoimmune conditions—time during which irreversible damage can accumulate
Of patients remain undiagnosed because current tests require active disease or specific conditions
Genetic markers identify predisposition, but most carriers never develop disease—we need better tools
Reading the Immune Response
The adaptive immune system is remarkably sophisticated—maintaining a detailed record of every pathogen and antigen it encounters. In autoimmune disease, specific immune cells become activated against the body's own tissues.
We're developing technologies to identify disease-relevant immune signatures, moving beyond genetic predisposition to detect active disease processes with greater precision than current methods allow.
Functional Signatures
Identify immune cells involved in disease, not just genetic risk factors
Advanced Technologies
Leverage sequencing innovations to profile immune responses comprehensively
Practical Solutions
Develop cost-effective approaches suitable for clinical adoption
# Immune Signature Detection
import imber
# Load patient sample
sample = imber.load_sample("patient_001")
# Profile immune repertoire
repertoire = imber.profile(sample)
# Analyze for disease signatures
result = imber.analyze(
repertoire,
condition="autoimmune"
)
# Generate clinical report
print(result.summary())
# → Signature detected: 0.87
# → Confidence: HighOur Focus Areas
We're pursuing applications where immune profiling can make the greatest clinical impact.
Autoimmune Diagnostics
Earlier and more precise diagnosis for conditions where current tests fall short.
Learn moreHematologic Malignancies
Enhanced monitoring through comprehensive immune receptor profiling.
Learn moreBuilding Tools for the Community
We believe in open science. Our team develops and maintains open-source software for immune repertoire analysis, making advanced computational tools accessible to researchers worldwide.
Explore Our SoftwareSingle-cell immune repertoire analysis
Deep learning for TCR analysis
Educational wiki for adaptive immunology—from fundamentals to cutting-edge methods
Explore →Interested in Collaboration?
We're seeking research collaborators, clinical partners, and investors who share our vision.